When it comes to malware protection, a common mentality on internet discussion forums is to run a "Cocktail" of security products. The various products that get recommended are usually free and often second rate.
I've ranted several times against that sort of advice here and even said that I've yet to lose a bet with anyone who thinks that this makes it okay to visit the seamy underbelly of the 'net. The bet is that I can find something malicious on their system that doesn't belong there.
Here's a graphic demonstration from this morning. This person was running:
Ad-Aware (Current and Up to Date)
Spybot Search and Destroy (Current and up to date)
Windows Defender (Out of date)
AVG (Free Edition) (Last updated 11/08/2009)
MalwareBytes AntiMalware (Free Edition) (Current and up to date)
Norton Internet Security 2006 (Very out of date - A trial edition bundled with the Compaq system)
He knew that Limewire was a bad idea but thought he would be safe.
....He lost the bet in thrity seconds