Self driving cars will be safer, that's a huge reason to me, lives will be saved. I don't like driving and will get one as soon as I can afford it. Especially when I am older it will be a huge advantage, think of all the older folks that can't drive or shouldn't be. Think of all the drunk driving accidents that can be prevented. If enough cars are self driving it will reduce congestion and make commutes easier. It will also save energy as self driving cars are more fuel efficient.
Yes, Uber drivers will lose their jobs, just like there are no longer people making buggy whips. Some jobs are lost, some are created and overall productivity improves with every advance in technology, it's a fact of life.
People will soon be wondering how they ever got along without them.