Posts by botchtowersociety

Hi ATJ, good to see you around.

BTS, check out the bolded section of the article i quoted previously...

Sounds fishy, although "stable disease" and "partial response" could be counted as a "success" in an aggressive resistant late stage malignancy.

What gets me is this: With all the real, legitimate, exciting research taking place, why is it that likely quacks get all the headlines?

he has a good idea, yes, but i am very far from convinced it work. 20 odd people in a non-double blind study with questionable protecols is NOT convincing.

The results may not even be statistically valid. I wonder if he worked with the FDA when he designed the trial protocols. I think he is highly suspect.

Another peculiar aspect of the Burzynski trials is that people have to pay to be experimental subjects and the amounts of money are not insignificant.

This is nuts, I have not ever heard of a trial being conducted in this way before. It might not even be legal.

The greed of big pharm has no bounds

Yet the next generation big cures are not coming from big pharm. They are coming from small biotechnology firms. Big pharm has become bureaucratic and has lost the ability to innovate. Many of the big companies are drastically slashing research and development, as well as outsourcing testing to contract research organizations. Big pharma is facing a patent cliff, where their most profitable compounds will be losing patent protections and will become generic status.

The only way big pharm will survive is by either licensing/co-developing with the small biotechs, or by buying them up outright.

Is the US government intentionally supressing a cancer cure?

No it is not. I am a cancer survivor, and was cured by radiation therapy. Is that not a cure? In addition to our current oncology arsenal, I can tell you there are many new therapies in clinical trials, right now, using many different mechanisms of action.

Cancer is not a single disease, it is many different kinds of similar diseases.

Cancer cells evolve rapidly, so they are highly adaptive. This makes a cure difficult. When the mechanism that Darwin discovered is fighting against you, it is a tough place to be.

There is no simple cure.

Let's see.....how many billions of dollars has the American Cancer Society and the Canadian Cancer Society collected over the last 50 years (supposedly) looking for a cure for cancer? Yet the standard treatment has not changed: chemo and radiation---two drugs which themselves, cause cancer.

This is not true. The standard treatment has changed considerably. Today we have marketed monoclonal antibodies, and various kinds of molecular inhibitors. All of these therapeutic techniques are far more targeted than traditional chemo and radiation therapy. Right now there are also immune system therapies like Provenge, and also selective VEGF inhibitors. This is just the beginning of what is coming to market in the next few years, if the FDA doesn't prove to be too great a hindrance.

There are a couple of small companies out there that are taking the antibody therapy concept one step further. They have developed a molecular linker technology where they take an engineered antibody and attach a powerful chemo drug. Unlike traditional chemo compounds, these are highly targeted conjugates. They selectively attach only to molecular receptors that are highly expressed in cancers. Once the antibody attaches to a cancer cell, it is pulled inside. Once inside, the cell's own machinery breaks the link between the antibody and the toxin, The toxin then kills the cancer cell. Traditional chemo can be likened to firing a machine gun into a crowd to kill one bad guy. These new therapies are like having a sniper than can kill the bad guy, while sparing the innocent.

There is a simple sugar compound discovered by a Russian scientist (Order of Lenin winner) that is currently in clinical trials in the US. It makes cancer cells more visible to the immune system, so that it can attack it.

Healthy cells have what is called a "guardian angel gene", that maintains genetic stability and induces cell death in the event of damage to the DNA. Nearly all cancer cells have this mechanism inhibited or shut off. There is a compound entering clinical trials that will restore the activity of this mechanism in cancers, which will reduce the rate of mutation, and also restore the cell's ability to undergo apoptotic death.

There is a novel small molecule VEGF/MET inhibitor being trialed in Canada right now as well. Early results are very promising in late stage patients with solid tumor metastases.

Also, there is now an inexpensive compound on the market that I believe, if used prophylactically, will drastically reduce the rate of incidence of new cancers, while, at the same time, protecting the brain from alzheimers, healing thyroid disease, lowering high levels of CRP along with the attendant cardiovascular benefits, reducing arthritis, irritable bowel syndrome, Crohn's and many other things. It may even restore some cognmitive function in autism. I know it sounds amazing, but it seems to strike at the root of what causes these things when we age: a runaway inflammatory response.

Skeletons in the closet=blackmail material.

Easy to control.

If true of course.