While that is not true as far as I can see, we could well have a computer program running in our brains that is like RAM in a computer and that this is our soul. Atheist hate this idea because computer souls would need programmer to set the code. And if this is true then we are forming new souls as we compute, and perhaps one day our computers will say hello to us, and ask where did I come from. Somebody tell Tyson that he is proving God, in his own image.
First of all, brains don't work like RAM. There could be a god. There could be a million gods. Why do you think that idea bothers me? If you show me evidence for it, we should investigate it. Same thing with a simulation. It could be true, but there is nothing to suggest it's true at all.
What is a soul anyway? Computing? That's just a metaphor. Unless you can tell me what a "soul" is, then you're not saying anything meaningful about them.