My Grey's Anatomy Connection - one of the teachers in my department - his daughter is married to Patrick Dempsey!
Seriously? (Sorry, couldn't resist.) As for Burke's nickname, how about McPants? Every week when my daughter and I are watching, we have to go through the cycle of who we love, depending on who's onscreen at the moment: "I love George!" "I love McDreamy!" But the one we always always always agree on is "We love Izzy!" And I want to say things about what just happened Thursday, but I don't want to ruin it for our overseas friends, so I guess we'll have to meet back here in one year to talk about when the thing happened between you know who and the other one and then there was the blood and the long look between him and her... Seriously.