whyizit,
There are a few reasons I avoid the 607 BC debacle in favor of other arguments:
(1) The average Jehovah's Witness doesn't thoroughly understand the prophecy as explained by JWs, so you must first teach them what JWs believe about it before you can demonstrate it is wrong.
(2) Publications that are difficult to acquire have been quoted by the WTS with brackets used to replace the author's dates with dates favorable to JW dogma, leading to a very confusing snarl that will tire out most JWs.
(3) Most JWs (in my experience) are not interested enough in history to follow along attentively as you show the Neo-Babylonian king's list and years of reigns as assigned by the WTS itself—which leaves a 20 year hole in history sometime between the accession year of Neriglissar and the accession year of Nabonidus if you start at 607 BC.
(4) The "hole in history" will invariably be explained by as yet undiscovered archeological finds. There is no general conception among JWs that dates must match archeological finds UNTIL archeology discovers otherwise.
For these reasons, starting with 607 BC is a fairly difficult thing to do with any but an exceptional JW. However, there are many other topics that are so straightforward and inarguable that I have not found it necessary to use 607 BC until after the JW no longer has such great confidence in the Governing Body's "spirit-directed" status. In such a state I have found JWs eager to learn more about the 607 BC error.
I don't think there is a way to explain how 607 BC can be ruled out (as a possible year for Jerusalem's destruction) to someone who has complete confidence in the channel that Jehovah is using to communicate with the world in our day.
Respectfully,
AuldSoul