Do you have any suggested routes? If there is good stuff to see in between? I don't mind splitting the trip to Vegas between two days
I really don't think there is an easy way to get from Reno to Vegas. I go to Reno and Vegas quite often. A few years ago we decided to drive from Las Vegas to Reno just to see what was in between. There really isn't much. There is no direct highway between them so you kind of weave from town to town to get there. The towns in between seem pretty poor and broken down. You go through towns like Hawthorne, Tonopah, Goldfied, and Beatty. Not much to see in any of them. If you read up on Ghost Towns before you go you might find some points of interest in some of these towns. If you are interested in flying saucers you can go to Area 51 which is about 50 miles north of Las Vegas. I passed it at night so I really get to look around.
Have you consider driving to Lake Tahoe while you are staying in Reno? Tahoe is a lot of fun. Probably too early to ski in November but there are lot of casinos with great food and good shows and all kinds of outdoor things to do. Virginia City is a fun day trip less an hours drive from Reno if you like old western things.
By the way I'm going to Reno next week. I still haven't decided if I an going to drive or fly because we have to go into San Francisco first to visit relative so I would wind up having to rent a car and from San Francisco to Reno anyway.
I have a Nevada map in my car. I'll look at it tomorrow and see if I can remember the exact route I took for Vegas to Reno.