I suppose adult onset anencephaly would qualify, if one stays in long enough and their brain is cut off long enough. The more submissive you are to the Filthful and Disgraceful Slavebugger and/or the hounders, the more at risk you are at developing this horrible disease. Those who do not develop it are at high risk of becoming apostates.
Additionally, I always had dry skin that was severely aggravated by the extremely dry environment in the Kingdumb Hell. And, the way the tons of lotion found their way into the Kingdumb Hells, I was not alone in that department. I have found that the severe chapping in my hands is no longer a problem now that I no longer go in the Kingdumb Hells (and yes, coconut oil works to prevent and treat this problem).