I know it's a chick flick, but since I'm secure in my masculinity, I'll give a huge plug here for Steel Magnolias. It is cram-packed with great lines!
Here's a couple that didn't even make the list of "memorable" quotes:
"Ice tea is the house wine of the South."
"He is a boil on the butt of humanity."
Here's a link to tons of others:
http://www.imdb.com/title/tt0098384/quotes
Oh, and a fave from the Princess Bride:
"You keep using that word," (inconceivable) "I do not think it means what you think it means."
om