Marking this thread to read the article tomorrow.
Snare....as always. That was interesting.
Brilliant Article On Aging
by metatron 20 Replies latest jw friends
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Qcmbr
All I got was fast every now and then + caffeine and green tea.
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metatron
I see stem cells as a workaround against the Hayflick limit.
There is isn't enough $ devoted to studying animals that live to extreme ages. Why reinvent the wheel? Evolution has figured it out already.
The thing that impresses me about autophagy is, if your cells aren't messed up and full of junk, how are they any different from young cells? How could you even distinguish an old cell from a young one? Why would they function any differently?
metatron
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scotoma
I eat a low calorie diet. I walk two miles a day. I do moderate weight exercises. I take some metformin. I never smoked. I hardly drink.
I pay close attention to mental hygene and stress to keep it down. I take a lot of OPC's. One day I'm going to wake up, take my vitamins, exercise, spend time with loved ones and die.
I haven't seen anything on the horizon that excites me about beating back the inevitable. I also haven't seen anyone who came back from the grave.
Who by worrying can add a cubit to their life.
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*lost*
Zed. lol.
edit to add: I forgto, lol. Something i find interesting is that sperm, constantly renews (until death of host, is that right ?)
Yet womens eggs (ovums ?) ya only get them once, and they deteriorate with age ( is that right ?)
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Vidqun
*lost*, what I last heard is that sperm also deteriorates as the person gets older. Some of the DNA sequences are lost, defective or doubled up. So I guess having children, the younger you are the better. Young people also have the energy to raise children, so that's nature's way of making sure the best genetic material gets through to the new generation.
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*lost*
Vidqim - Thank you.
Old men ( like really old, pensioners ) can father perfectly healthy kids.
Women can produce up to a certain age limit ( menopause ) but, the risks of child being healthy is higher, the older the woman gets. ( in theory, I know now with the aid of science, auld grannies are having kids these days.)
I haven't researched it. It just popped into my head last night while reading snares comment.
Snare. Would you start new thread titled the Hayflick Limit. i just had a quick ganzy and it's really interesting.
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snare&racket
I have medical exams in 7 days otherwise I would.
why not go for it yourself ? X
you guys are all intelligent and capable, I don't understand why so many are content with dipping in to bar talk science, get a decent textbook and devour it. I assure you it is more exciting and amazing than any pseudo science.
BIOLOGY by campbell and Reece is a great place to start.
Right... Back to the scary revision.
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*lost*
good luck for exams
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Vidqun
*lost*, here's an interesting article on the deterioration of sperm with old age. The advice of the one that did the experiments. Bottom line: Do not delay having children. "There are consequences of delaying fatherhood."
National Geographic News: Men Have Biological Clocks Too, Sperm Study Says
In the study, Wyrobek, Eskenzai, and colleagues examined the genetic quality of sperm from 97 healthy, nonsmoking men between the ages of 22 and 80. The men were current and retired employees of the Livermore laboratory.
The study sample included at least 15 men from each ten-year period from 20 to 60 years of age and 25 men 60 to 80 years old.
In earlier research on the same sperm samples, the team found that sperm count, mobility, and the ability of sperm to move in a straight line declines with age. The new research shows that mobility has a high correlation with DNA fragmentation.
The new study also found that men face increased risk of fathering children with achondroplasia, a genetic mutation that causes a form of dwarfism.
The condition stunts bone growth; affected individuals have short arms and legs and grow to only about 4 feet (1.2 meters) tall.
As women grow older, they are more likely to give birth to a baby with Down syndrome. Not so for men, apparently.
However, the study found no general correlation among male age and chromosome changes that cause Down syndrome.
Even so, 4 of the 97 men were at increased risk for transmitting multiple genetic and chromosomal defects, according to the results. Age may have nothing to do with these subjects' condition, though; one was in his 20s and three were over 60.
Interestingly, Wyrobek added, the sperm in the Lawrence Livermore sample showed no increase with age in Apert syndrome, a disfiguring birth defect.
However, the likelihood of fathering a child with Apert increased with age in men from inner-city Baltimore, Maryland, tested by researchers at the Johns Hopkins Medical Center for a different study.
Wyrobek cautioned against reading too much into the Baltimore study group's results, since they were all from men who lived in the same area.
"There're other things going on besides age. … It could be socioeconomic, or diet, or ethnicity."
Further studies, he added, will examine the Apert syndrome factor in greater detail.
Don't Panic
Craig Niederberger is a urologist at the University of Illinois in Chicago. He said the research findings are interesting and warrant further study. But he cautioned that the technique used to test the DNA of sperm is new and controversial.
"Older men should not yet be concerned about fathering children. The evidence is still inconclusive," he said.
According to Niederberger, who is president of the Society for Male Reproduction and Urology, researchers need to examine the integrity of sperm DNA with other methods before sounding alarms about male infertility.
Nevertheless, he said, the finding that a genetic mutation that leads to dwarfism increases with age is cause for "some concern. We ought to pursue it."
Wyrobek said the research raises more questions than answers. But it suggests certain kinds of DNA damage and genetic defects go up with age.