1) the signs of the times are qualified:
LUKE 21:
Then he said to them: “Nation will rise against nation, and kingdom against kingdom. 11 There will be great earthquakes, famines and pestilences in various places, and fearful events and great signs from heaven.
So it's not just earthquakes, famine, pestilence it is great famine, earthquakes and pestilence COMBINED with fearful events and great signs from heaven.
2) Second point is that he says the persecution would happen before these events(earthquake, signs from heaven etc..):
12 “But before all this, they will seize you and persecute you. They will hand you over to synagogues and put you in prison, and you will be brought before kings and governors, and all on account of my name. 13 And so you will bear testimony to me.
Jw's combine these to be happening at the same time such as the persecution in Bulgaria, WW2, etc.. but the bible says AFTER the persecution these things will happen. That's about it.