Are jobs a concern? Usually, Jacksonville area offers good job opportunities and lower cost of living. The houses are cheaper there, the beaches & fishing is great, and the cost of car & home insurance is lower too. It is like Fall there in the winter.
The further south you go, the higher your house & car insurance.
Orlando is super hot in the summertime. The whole state is hot in the summer, but the middle of the state swealters. Near the coast is cooler and has breezes & more afternoon showers.
Fort Lauderdale & Miami are like mini NYCs. A lot of crime and uninsured drivers there. But, there are jobs. If you are a millionaire, then these areas are great.
I don't know how the jobs are in Tampa. It is a big area, so you should get the job before you buy the house.
Honestly, I'd rent a place for a few months before buying.
And, if you don't have to work, rent a house in Islamorada. That's paradise.
Skeeter