Never was an elder, and I didn't have to resign as MS, got the boot, which was fine with me at the time...
...But a friend (at the time) stepped down for some of the same reasons you list. And when he got blowback from the rest of elders, he stood up to them and said that his family came first and foremost, and it was his duty as head of the house to make sure he presided over them in a fine manner. He knew that he could not carry the burden and didn't really care what they thought or did, he was doing what he had to do to manage his sanity, his health, and serve his family. I always respected him for that. To not only stand up to the peer pressure but to know your limit and when to say, 'it's time to pull back and focus on what's really important' instead of trying to juggle everything the WTS throws at elders.