I've lived in Portland, Oregon and Kennewick, Washington.
Portland - Grey and rainy alot, but lush and green because of all the rain. Largest bookstore in the country (Powell's) and fabulous coffee. Lots of people interested in animal rights and the environment, very liberal. Too much traffic, too much crime and housing's expensive. But it's a cool place to live!
Kennewick - Eastern side of WA state, desert-like - don't think sand and cacti, think tumbleweeds and brown hills - not attractive at first but you grow to love the big open sky, the beautiful sunrises and sunsets and the adorable quail (especially when they have their babies each spring!). Not a great library, but they did remodel and the main branch is great, comfy chairs and a fireplace. People tend to be pretty conservative. Coffee has definitely improved since I moved here - there used to be only one lone Starbucks, and it was new and untested at that. ("Grande, half-decaf, non-fat hazelnut latte please." "Huh??") But it's grown and improved, and we now have the requisite one coffee place per three blocks in the main parts of town. Some are good, some are not so good, but they're trying! :-) Weather is GREAT - sun 300 days a year, and even the hottest days aren't bad because it's such a dry heat and because everybody has air conditioning - in Portland when I was growing up if it was 90+ we all just wilted and laid on the couch in front of strategically placed fans. LOW housing prices (I'm drwatson's wife, see his reply) and we have the strongest economy in the state right now. Not that it's easy to get a job, but it can be done. Low crime, hardly anything even approaching a traffic jam other than going between Richland and Kennewick at 5 p.m., and even that takes about 10 minutes instead of 5, so it's not bad. And you never, ever have to parallel park! This is very cool to me because I suck at the afrore-mentioned skill. I think I've had to parallel park one time in 7 years, and then I just got out of the driver's seat and let my friend do it. Okay, I really do suck, at least I admit it! :-) Local produce is available in the spring/summer both at farmers' markets and in local grocery stores - great corn, amazing cherries and apples.
Well, now you know what I care about (good coffee, good books and yummy cherries) - I suppose you could consider that you're living next to a (decomissioned) nuclear plant, that there's a chemical depot about an hour away that has tons of chemical weapons stored that if they ever get out will kill everybody...but if you're running away from chemical fall-out, at least you won't have to parallel park to buy your staples of bulk cherries and lattes!