Henry
Poor Henry! He can't talk, he's not deaf, and he doesn't know Sign Language. He wouldn't be able to talk to people at their doors or give talks. Even worse, he wouldn't be able to answer the final two baptism questions at the Assembly.
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Broom Hilda
On the plus side, she always wears a hat, which is a sign of subjection. However, she would never be able to give up celebrating Halloween. Also, she IS a Witch and and Witches will have no place in God's new system of things. Besides, her broom doesn't have four doors and thus wouldn't be practical for field service.
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Calvin AND Hobbes
Can you imagine how annoyed the Elders giving talks would get if they had to look at Calvin & Hobbes making faces at them during their (the elders) parts? The picture on the right shows what happened when Calvin & Hobbes snuck into a Congregation Picnic.
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Feel free to add your choices to this list of Comic Strip characters not cut-out to be JWs.