TD: one of the Hb based substitutes in competition with Hemopure and Polyheme was in fact made from donated human blood whose shelf life had expired. (Hemassist by Baxter Laboratories)
You are correct that Hemassist was made from expired human blood, but so was Polyheme (made by Northfield labs). Polyheme has also been used on JW patients.
Hemassist clinical trials, in the late 90s, were halted when the subjects died at a much greater rate than those who didn't receive it.
In fact, all the blood "substitutes" that have been tried on JWs have proven to be less effective than blood itself