You start with your title, "What do you think I should do?" You make a strange statement: "...looks like a Lesbian, sounds like a Lesbian, and lately is starting to feel like a Lesbian."
Then, some give a serious answer in the same kind of tone, and you blast them:
Ignorance: When a fly walks on your shoulders, do you just leave it there and make it feel like home?
James: We are not worried about catching anything, and we are not prudish. We don't want a reason to worry about it.
I know you are seriously asking for help, but YOU DID ASK and you started out with the goofy tone about lesbians, so lighten up.
And seriously, the suggestion to cock block her by sitting in the second seat from the end where your wife will sit on the end is a very good one.