Hooby - You linked a pseudoscientific article written by a creationist charlatan who either didn't understand the paper he/she did violence to or did understand it and did violence to it deliberately.
Then we have to add another level of deceit when creationists like yourself quote the article written by the charlatan even though you don't understand the article and haven't read the original paper to see for yourself how your creationist charlatan is doing violence to it.
The article is about how rare mutations contribute to the risk for disease. It also explains the 'excess of rare variation across the exome' by examining the population explosion that occurred around 5000 years ago.
Nowhere in the article - not even on one occasion - do the authors mention your bogus term 'genetic entropy'.
Please read the article before you try to tell us what it is about.