When I was a dub, I found the issues that bothered most worldly people were connected with children, i.e. how we could allow a child to die for want of a blood transfusion, and how cruel it was to prevent a child from celebrating birthdays and Christmas.
I am amazed how many people I speak to have absolutely no idea about the fundamental beliefs of JWs. Despite being contacted by JWs many times over the years, they still think JWs believe the end of the world is coming and they are going to heaven. They have no idea about an earthly hope.
Many of the issues that worldly people had when I was a dub, and still seem to have, were totally inaccurate things such as thinking JWs are not allowed to accept any form of medical treatment. Also, as already mentioned, that JWs don't believe in Jesus (due to not celebrating Christmas).
So much for the world wide preaching work!