LOL no prayer in the world can compare to a heroic dose of Psilocybe Mushrooms. You may pray yourself into a dizzy tizzy, but it is absolutely NOT the same as a psychedelic experience.
Now, on the other hand, combining a strong structured ritual/prayer with psychedelics like psilocybe mushrooms, in a responsible, safe setting can certainly boost your prayers, if you're into that. There can be many spiritual and psychotherapeutic benefits to psychedelics, given they are taken in a safe and setting.
Also, comparing cocaine, crack and booze to plant teachers like psychedelic mushrooms, catcti, Ayahuasca, and other plant teachers is also a common bias.
Psychedelics are not for everyone and there is no substitute for your own sobering hard work in controlling your mind, connecting with your inner Divine, and working through life's challenges without any external consumption.
However, there is also NO substitute for psychedelics and the psychedelic experience.