Sin is a religious word, it can't really have any bearing in a discussion of the process of disease and death.
We actually know what causes many diseases in minute detail, and even conditions once thought to be the result of nurture or upbringing apparently have organic roots, such as schizophrenia and bipolar disorder, and autism.
We're probably going to find, as we discover more about the brain, that many behavioral problems have organic roots, even if they're triggered by a stressful and poorly nurturing environment. Already, depression, anxiety and some anti social behavior is being well controlled in mice by treating them with enzymes that prevent the RNA in our brains from altering in detrimental ways.
It seems that along the course of our evolution into humans, we have picked up about 50 or so endogenic viruses that made themselves part of our brain or nervous systems RNA, and exposure to stress or certain retro viruses, which are viruses that rewrite our RNA into DNA, usually always with very nasty results, particularly in childhood, trigger those endogenic viruses and cause all sorts of diseases, like multiple sclerosis, Parkinsons, schizophrenia, and bipolar disorder, and possibly other diseases that we associate with anti social or harmful behavior. There is still much research to be done in this field.
It's totally conceivable that most of our "bad behavior" has organic origins and the reason we've labeled some behavior as bad, neglectful and sinful is simply because not nurturing our young and being hostile to others creates an environment in which old endogenic viruses, which are viruses that literally are lying dormant in every human being's brain, are much of the cause of "sin".
It's interesting to me that one day we may literally treat "sin" and crime as an organic, treatable disease, and simply treat it medically, on the genetic level. If we get rid of sin as a medical treatment, will we need religion, or a God who can absolve us of it?