If you can somehow get this sister's address, send her an anonymous letter. Word it in a way that does not state in absolute terms (unless this man is on an official pedophiles list - Megan's Law) that this person is a pedophile, but that you have information that leads you to believe that her children may be in danger if she continues her relationship with this brother and allows him to move in with her and her children. Keep a low profile and watch what she does after she gets the letter. Does she pull closer to the man, or does she show signs that she might be having second thoughts. You may see a combination of both responses.
Also find a way to inform the police. A telephone call is often the best way. Yes, they may capture your phone number, but that is more for your protection than just an easy way to hunt you down. Police have been getting tips for decades using 800 toll free lines - and all show the calling number. I've never heard of a non-involved tipster being outed by calling one of those toll free numbers. It's not in the police department's interest to get a reputation for hunting down tipsters - soon they would have none. An anonymous letter to the police department would be a second choice.
If the man is on an official pedophile list, don't even think twice - call them. Tell them you know he is a registered offender and that he is having a relationship with a single woman with small children. Don't accuse him of anything, just tell the police that you feel someone in authority who has the law on their side (and therefore protected from slander suits) should make contact with this woman, make sure she knows that her children are in jeopardy, and that the man has restrictions. Don't mention how you know - only reveal that if they really press you.
If they do press you, then tell them that there are records maintained by the elders that will likely prove that they've known about this man but have failed to inform the lady or anyone else in the congregation of the potential threat that this man is to their children. Tell them that is standard procedure with elders because that is what the Watchtower organization orders them to do. That is why you are calling them because you doubt that any of the elders would follow the law and do it themselves no matter how critical the danger is for that woman and her children. With luck, if they can verify that the man is in fact a registered offender, then they can get a subpoena and confiscate those records. Who knows? There may be others in Hall that fall in that same category.
Some states have laws that protect anyone who reports potential child abuse. You might want to ask the police or child protective services if your state offers that protection. If this fellow has a criminal history (in prison or an extended stay in jail), then you should do everything to keep your identity unknown. Men who have been in prison for an extended time spend much of their time learning and devising ways to "get even" without getting caught. So do be careful.
Having been involved in law enforcement many years ago, I am somewhat familiar with the process of handling "tips." Sometimes the police will route you to a special desk that handles these kinds of calls and knows exactly how to handle them. Ask the police if they have such a "tip" desk. Be honest with whomever you speak to and let them know that you are fearful (whether you are or not) about what might happen if this man finds out who you are. Not only that, but that you will likely suffer repercussions from the elders at the Kingdom Hall because of their "protect pedophiles" and "punish anyone who acts without their permission" policies.
Above all - think first of the children. Imagine them as yours not hers. Then do what you know must be done.
JV