Space Madness, go argue on your own, you are just being confrontational. This is not a debate its a chat. Nobody is promoting it as a treatment and there is science and research into its role in sleep and medicine whether you knew it or not.
" After a pause of nearly 40 years in research into the effects of psychedelic drugs, recent advances in our understanding of the neurobiology of psychedelics, such as lysergic acid diethylamide (LSD), psilocybin and ketamine have led to renewed interest in the clinical potential of psychedelics in the treatment of various psychiatric disorders. Recent behavioural and neuroimaging data show that psychedelics modulate neural circuits that have been implicated in mood and affective disorders, and can reduce the clinical symptoms of these disorders. These findings raise the possibility that research into psychedelics might identify novel therapeutic mechanisms and approaches that are based on glutamate-driven neuroplasticity."
Nature Reviews Neuroscience 11 , 642-651 (September 2010) | doi :10.1038/nrn2884
Sleep.... we know seretonin is involved, we know DMT alters seretonin levels, there is research showing its interaction with REM sleep. Whether we are metabolising DMT to increase 5HT in REM sleep is EXACTLY what I want to know.
"Results show that daytime serotonergic psychedelic drug administration leads to measurable changes in PSG and sleep power spectrum and suggest an interaction between these drugs and brain circuits modulating REM and SWS."
Psychopharmacology February 2008, Volume 196, Issue 2, pp 315-326
WILLOW: There are studies on psychadelics indicating their medical use in addictions, anxiety and depression. Interesting stuff. Stigma and ignorance is holding back research, it would be interesting to see the potential for such chemicals. I am sure in the future, at the very least there will be more research. But I do think it should become more scientific and less anecdotal, just because its the best method of assessment. It is important to say willow that even though there is research confirming the relation to mood states, we just don't know enough yet.
"The present study investigated the effects of ayahuasca in anxiety, hopelessness and panic-like measures through a double-blind protocol in Santo Daime members. Acute ingestions of the brew significantly attenuated hopelessness and panic-like parameters as detected by BHS and ASI-R psychometric scales, respectively.
Taking into account this indirect agonist action of ayahusca at the monaminergic system, including the noradrenergic but preferentially the serotonergic system, we might speculate that the reduction of BHS and ASI-R psychometric parameters observed in the present study were mediated at least in part by this mechanism. This suggestion is supported by the fact that the majority of antidepressant/antipanic drugs also enhance noradrenergic and serotonergic functions, either inhibiting noradrenalin and serotonin reuptake, such as the tricycle antidepressants, or selectively inhibiting serotonin reuptake, such as the widely used selective serotonin reuptake inhibitors."
Journal of Ethnopharmacology Volume 112, Issue 3, 25 July 2007, Pages 507–513.
Anyone with psych issues may come to harm, as with many drugs including psychadelics. Anecdotal evidence and ayahuasca/ dmt experiences are becoming more common and recreational, hence why we need more real research so that the only source is not the internet and word of mouth. Obviously, taking psychadelic drugs is unadvisable medically, but in the REAL WORLD people do take it and I am interested in what people have experienced. Documentaries on NETFLIX and well known interviews mentioned here are being discussed and listened to. Stigma and ignorance may force research into the hands of the unqualified and that is dangerous.
Snare
