I see three factors in your grey fog.
- You are not being treated properly by your wife.
- You feel like you are at an impasse with your career.
- You may have a brain chemistry that requires drugs to readjust.
1. Perhaps your wife is bored with your depression, and decided to go have fun regardless. THAT IS NOT YOUR FAULT. She should still be living with integrity and compassion. Is she a shallow thinker? I am a jealous partner and when I sense a threat, I go along. I want to know what I am up against. If I were you, I would go along on her jaunts, even if you don't feel like it. Face what you are up against.
2. When I get bored with my job, that is a signal to move on and grow. Who said you had to be promoted in the position you are in? Take a Career Evaluation course to help you consider other jobs/opportunities that might be out there, and go for it! Every one of my job moves were positive for me and my career.
3. Drugs have improved immensely in the last ten years. It is worth it to give another try. Many of the new drugs are non-addicting and have fewer side-effects. Find a good doctor and persist until you find the right combination.