I can't help but feel like he's pointing to a current man, saying that there are only x mutations that could be made in a given amount of time, and the dilemma is that not enough time has passed to do that. But doesn't this require knowing the starting point?
You've got their line of reasoning down pat. And I agree with you, to throw around specific figures you have to a have a specific starting point. Without the DNA of the human-chimp ancestor we really can't empirically say just how many mutations occurred to result in modern man. To compare humans and chimps you'd also have to figure that chimps have diverged from that shared ancestor as well. By how much? Once we've got all the genomes of humans and chimps sequenced we'll get a better idea.
Methinks the YECers are saying: We'll choose a starting point of 10 million years ago. So we're giving the process nearly double the time you evolutionists say passed from the human chimpanzee split. But even with all that time the limit is still a puny 1,667 substitutions. In your face Darwin!
Haldane did that theoretical model in the late 50s before the boom in good DNA data. They like to have things both ways. Evolution is too slow for humans to apes but its totally possible to have that massive burst of speciation in the shorter time from the Flood.