REV 16:6, 17: 1-6, 18:20-24 Tells us Babylon was drunk with the blood of the prophets, no one else can be said to have persecuted theOld Testament and 1st century prophets. SO only Jerusalem fulfilled that decree and Messiah himslef in Matt 23:31 said it was Jerusalmethat had killed the prophetsand in verse 32 that Jerusalem was about fill the cup of their sin by continuing persecute those sent to her namely the1st century Apostles. REV 17 tells us she had continued to fill her cup by persecuting the propets of old and those who followed Messiah in that 1st century generation.Matt 23:35 SHows usJeruslaem wa sguilty of ALL the blood shed on earth and in verse 36 judgement would comeupon Jerusalem in his generation and itdid come to pass in 70 AD exactly as Messiah and the prophets of old had warned. Finallythe Great city Babylon was also known spiritually as sodom REV 11:8 and the only city that is ever called sodom was Jerusalem Iasiah 1:10,JER 23:14; EZEKIEL 16:44. Babylon is also where the Lord was cruciifed. REV 11:8 Messiah was crucified in Jerusalem. The Jews murfdered stephen, beat peter and john, stirred up persecution against those 1st century faithful ones in Jeruslaem
InROmans 10:18, 16:25-26, the apostle confirms that the gospel had in fact been preached to all the nations in the world by about 60AD and in COlossians 1:5-7,23 about63AD, he said the gosepl had been preached to every creature under heaven. In Titus 2:11 he said the Gospel had appeared to all men. Meaning the fullfillment of what Messiah said came true before the destruction of Jerusalem in 70 AD. Babylon was first century Jerusalem. The Harlot was also Gid sunfaithful covenant people of that 1st century generation