@Dis-member
These numbers are not all that unreasonable. They spend over 70% percent on the program. Typically a disease fighting organization doesn't spend the the lion share of its money on research grants alone. There is a lot of components of a program: education, financing treament, research, etc etc.
Perhaps 27% is a tad low, i would expect it to be between mid 30's to 40 percent, like the National Cancer Institute, but again i don't think it's unreasonable. The salaries are not unresonable either; whether we like it or not, these organizations need talented people leading the way, people who have good networking skills and that are able to follow through on a vision.What also happens sometimes is that these research grants are given to research teams who demonstrate worthiness of receiving the grant. If not enough teams meet this standard, the organization will invest some of the monies in other areas of the program.