Have scientists ever been able to recreate or virtually witness a Macroevolution type jump that "transcends the boundaries of a single species"?
@Jacob
I think that many have answered your question in various ways, and I'd like to answer it myself also... but I am just curious as to what prompted you to ask? Do any of the answers ring true for you?
As Cofty mentioned the real answer to your question is 'no'... but then again the question (IMHO!) is not framed correctly (please excuse the arrogance of that statement!).
I think it would be fair to say evolution can only truly relate to populations not individuals; this is why the question does not seem to be framed correctly. Each individual in a population must be able to breed with the rest of the group, any massive genetic abnormalities would result in a dead end (quite literally).
The way the question is phrased makes it sound like you are asking if science has ever witnessed a 'dog giving birth to a cat'... and that just cannot happen.