The "direction" of science (if one wants to assume it has a direction) points towards the unknown, right where it should.
The closest science comes to the main thrust of your post is sociology... and I am yet to see anything suggesting " more and more MATERIAL comforts and luxuries" are the solution to our problems. Why do you posit 'science' suggests this path?
As the majority of American's believe in the immortal soul you would think the USA would be one of the happiest places on the planet... oh wait... it's not, not by a long shot. Why is this?
As for your little comment about 'some feel' the brain is the source of our intelligence, I am not quite sure what you are driving at? I assume you are suggesting our intelligence comes from the soul? In which case why are humans not born with fully formed personalities? If it is because the brain is not ready, then you are suggesting the intelligence of the soul can only grow with the brain, in which case you may as well do away with the soul bit is not adding anything.
What are the implications of intelligence coming from anywhere other than the brain? Why, if intelligence is from a soul, does dementia have any effect on our aging populations? Why is a "soul brain\intelligence" affected so profoundly by damage in the brain?