I find genetics fascinating. It's not always the gene, but how that gene is expressed.
I have a cat like the one in the video. She is a tortishell dilute with white. Both torties and calicos have one black color gene and one orange color gene, and as they said, are almost always female. In Lizzie's case she also carries the dilute gene, which distributes the color more along the hair shaft, making the color lighter, grey and peach instead of orange and black. She has one white spotting gene. White is not a color gene, like black or orange, but something that overlays the color, no color equals white. If she had two white spotting genes, she would have more white and the colored patches would be larger, making her a calico. You can see where two two colors switched, often it is down the spine, and down the front of her face. She has what they call a split face. Some split face cats have two different color eyes, it is somehow connected to the coat color.
She is also the smartest cat I have ever known. She does a number of tricks, likes to steal things and is always trying to think of ways to get me. She lays in wait under the bed and grabs my ankles, and sneaks up behind me while I am sitting on the couch and smacks my head. She will patiently wait for me to get in bed and run up the moment the covers start to come dow, reach her paws in and goose me, then run off like a bat out of hell. I'd like to know what gene causes that.