Doctors nowadays don't recommend blood transfusions unless there is a specific need for it.
For example, if you have a very low hemoglobin level (70 mg/L or less) they would recommend it, especially if you are symptomatic. There are alternatives, of course, such as boosting your iron intake with supplements or diet.
Fractions are more of an individual thing. For instance if you are a pregnant female with Rh negative blood, they usually recommend that you have an injection of RhoGam in the third trimester and within 72 hours of delivery, to protect the baby and future pregnancies from exposure to antibodies against Rh positive blood.
Babies who are exposed to these antibodies can have varying degrees of erythroblastosis foetalis, which causes severe jaundice, and used to require exchange transfusions. Now high intensity ultra violet lights are used to treat jaundice, and exchange transfusions are only done on a very rare occasion.
People who require clotting factors (hemophilia, von Willebrand's disease) are allowed to take these fractions. Incidentally Factor XIII was one of the first blood fractions permitted by the WTS in the treatment of hemophilia as early as 1974 (w 6/1, QFR). The irony here is that while the WTS forbids transfusions that come from one donor per unit and compare it to fornication/adultery, they do permit fractions that are manufactured using "large pools of donor blood" - would that be equivalent to an orgy if you extend the WTS's beloved sexual immorality comparison?
There are lots of blood fractions - anti tetanus toxoid vaccine, anti venoms for snake or spider bites (separate preparations for each type of venomous snake/spider).
Your decision whether to accept the treatment or not would likely depend on the severity of the outcome if you chose to not accept treatment. For example, will you or someone you love die or be permanently maimed if you don't? You aren't required to martyr yourself anymore, and you aren't required to sacrifice your spouse or children anymore. Keep that in mind when making your decisions, and don't let some bullying publishing company coerce you into making a decision that will cause regret to yourself or to loved ones.