I love science. What I hate is greed and blind trust.
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Was A Cancer Cure Quietly Eliminated?
by metatron 68 Replies latest jw friends
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JeffT
If you believe the people peddling these BS claims are not motivated by greed I've a business proposition for you.
As far as the docs paid for by the tobacco companies: People in the medical profession are like all other people. A few will do anything out of bad motivation. There are over 600,000 doctors in this country. A few work for tobacco companies, a few have other problem. Are you going to judge the barrell by a couple of bad apples?
BoTR, I had a bad experience with a lawyer a few years ago, should I conclude that all lawyers are greedy jerks?
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Witness 007
Well I just read Mebendozol {Vermox} has ceased production as of Dec 2011 in the USA Wiki says "No reason or explaination" was given......it will probably come out in the future as a "new" cancer drug at $300 dollars a box.
Like I said Chemo is like using an Atomic bomb to demolish a house......isn't there anything better after 80 years of study and Billions of dollars.....oh, thats right, they told us not to eat so much red meat....good work!
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botchtowersociety
You guys should set your uninformed biases aside and listen to Jeff. He knows of what he speaks. He has been around biomedical research his whole life. His father won a Nobel Prize for his work in bone marrow transplants. Thousands of people are alive today because of it.
If someone ever found a magic bullet for curing cancer, they'd pour everything they had into getting it to market...and their investors too. That market would be worth $100 billion a year in sales. They'd be rich beyond the dreams of avarice.
But the fact is this: cancer is very hard to deal with. It isn't a single disease. And, even within one particular cancer type, there can be many different kinds of mutations. You find something that works really well in one kind, and the cancer can evolve resistance. Every case of cancer is unique.
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Disillusioned Lost-Lamb
I do believe a "cure" can be found, but it is not in treatment, treating cancer kills more people than the disease itself; the "cure" is in prevention.
In basic terms, cancer is a fast growing multiplication of cells; so why do these cells get a message to grow out of control without stopping?
When we find the answer to that, we find the cure.
The truth is there's already a mountain of evidence to support three simple things, 1-toxin elimination, 2-sugar/carbohydrate moderation and 3-ph balance, can cure most disease.
1-Eliminate the cause by routinely cleansing your system (while trying not to put the nasty stuff back in) Toxin build up can make you a walking chemical lab; some mimic natural hormones that give the body mixed signals, such as signaling normal cells to grow out of control while telling others to shut off when they shouldn't.
2-Elminate the food source by moderating your carbohydrate consumption; cancer feeds on sugar and a lot of other diseases are caused by inflammation, which is caused by the over consumption of carbohydrates, especially processed and genetically modified one's.
3-Balance your body's acid/alkaline level and diseases such as cancer cannot survive; ph balance can mean the difference between a sickly individual or a healthy vibrant human being, even if you live a healthy lifestyle you can still be out of whack.
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cofty
treating cancer kills more people than the disease itself;
No it doesn't, many people die during or despite treatment. Why should that surprise anybody?
why do these cells get a message to grow out of control without stopping?
Genetic mutation. I am sure the ultimate solution will be found in gene therapy.
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botchtowersociety
I am sure the ultimate solution will be found in gene therapy.
I suspect you are correct. We can already use transcription factors to rewrite any gene we choose in the lab, but the big challenge is systemic delivery in human beings. We need to figure out a high-percentage way to get past the membrane.
Another solution, that could end up being a magic bullet (we can dare to hope!), is the TP53/P53 pathway. That is the guardian angel of the genome, and is implicated in just about all cancers. It is either mutated so it doesn't function (in about 50% of cancers) or blocked (all the rest). Restoring function leads either to gene repair or to apoptosis.
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cofty
BTS - I read a very interesting book by Matt Ridley called "Genome". Ridley is or was the head of the Centre for Life in Newcastle England and the book is a whistle-stop tour of the human genome.
One chapter is about the genetic mechanism of cancer. He describes the multiple safety nets in the cell that prevent it from dividing out of control, in particular the TP 53 gene on chromosome 17 that you mentioned above.
Some genes, called oncogens, cause cancer if they become jammed on wheresas tumour-suppressor genes like TP 53 cause cancer if they get jammed off. P53 the protein produced by TP 53 is now one of the most famous products of the Scottish city of Dundee where it was discovered by David Lane.
Take the case of colorectal cancer which I have become an amateur authority on recently for obvious reasons. It begins with a mutation to a tumour-supressor gene called APC which casues the development of a polyp. If a second mutation happens jamming on an oncogene called RAS the polyp will develop further into an adenoma. A third mutation of an as yet unidentified tumour-suppressor gene will cause it to go on to become a full-blown tumour.
The big danger comes from a fourth mutation tnis time in the TP 53 gene.
TP 53 codes for the P53 protein that normally has a half-life of 20 minutes but on receipt of a signal production rises rapidly and destruction of the protein almost ceases. The exact source of the signal is still unknown but it is thought to be connected to DNA damage. P53 tells cells to either stop proliferating or to kill itself.
Some researchers believe that chemo and radiotherapy do not primarily destroy cancer cells at all. Instead they casue enough damange to DNA to alert P53 to go into action. This means that these treatments actually work like vaccines by helping the body to help itself. This would mean that instead of looking for agents that kill dividing cells doctors need to focus on agents that promote cell suicide.
It follows that if TP 53 is broken tumours will remain unaffected by radio and chemo therapy. If this can be proven and widely adopted it may help prevent some patients enduring treatments that will not be effective in thier case.
If only it was as simple as drinking baking soda Botzwana!
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botchtowersociety
Some researchers believe that chemo and radiotherapy do not primarily destroy cancer cells at all. Instead they casue enough damange to DNA to alert P53 to go into action.
I was not familiar with this. It certainly isn't a consensus view. The mechanism of action of most chemo drugs is generally very well understood.
Regarding P53 activation, researchers thought a class of compounds known as nutlins showed promise. Unfortunately, it tunred out that nutlins kill more than just cancer.
However:
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still thinking
Well I just read Mebendozol {Vermox} has ceased production as of Dec 2011 in the USA Wiki says "No reason or explaination" was given......it will probably come out in the future as a "new" cancer drug at $300 dollars a box.....Witness007
YUP
Oncologic treatment potential
Several studies show mebendazole exhibits a potent antitumor properties. MZ significantly inhibited cancer cell growth, migration and metastatic formation of adrenocortical carcinoma, both in vitro and in vivo. [ 5 ] Treatment of lung cancer cell lines with MZ caused mitotic arrest, followed by apoptotic cell death with the feature of caspase activation and cytochrome c release. [ 6 ] MZ induced a dose- and time-dependent apoptotic response in human lung cancer cell lines [ 7 ] , and apoptosis via Bcl-2 inactivation in chemoresistant melanoma cells. [ 8 ]
[edit] Discontinuation in United States
The last manufacturer of mebendazole in the United States, Teva Pharmaceuticals, announced on October 7, 2011, that they have ceased manufacture of this product. As of December, 2011, it is no longer available from any manufacturer in the USA. No reason was given for this discontinuation. [ 9 ]